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Mitochondrial copper depletion can inhibit mitochondrial oxidative phosphorylation and target sex determining region Y-box 2/octamer-binding transcription factor 4 positive cells (SOX2/OCT4+ cells) with highly metastatic properties in TNBC by suppressing their metabolic reprogramming, which may potentially inhibit TNBC metastasis (180)
[DOI] [PubMed] [Google Scholar] Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS
10.1016/0896-6273(93)90115-8 [DOI] [PubMed] [Google Scholar] Tang J, Robertson S, Lem KE, Godwin SC, & Kaler SG (2006)
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