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In some cases, elevated serum MMA (and tHcy) concentrations have been reduced by vitamin B12 therapy, thus confirming vitamin B12 deficiency (Lindenbaum et al., 1990

Journal of Cheminformatics 15 (1): 76.

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[21] Furthermore, an animal study in ewes demonstrated that a B 12 , folate and methionine restricted diet around conception, resulted in offspring with higher adiposity, blood pressure and insulin resistance which could be accounted for by altered DNA methylation patterns