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*Correspondence: Julien Baruteau, [email protected] This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In a staphylococcal infection setting, riboflavin has demonstrated its anti-inflammatory property through reductions in NF-B, COX2 (cyclooxygenase 2), TNF-, NO, IL-1 (interleukin 1 beta) reducing iNOS (inducible NO synthase) synthesis, as well as an elevation in anti-inflammatory cytokine IL-10 (interleukin 10), and modulation of MCP-1 (monocyte chemoattractant protein 1) function, a potent chemoattractant ( On the other hand, riboflavin has an indirect anti-inflammatory activity through vitamin D metabolism

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10.1080/10408398.2017.1366892 117 SalamannaF.BorsariV.ContarteseD.AldiniN

Most astrocyte network termini, such as this terminus in prefrontal cortex, do not show detectable streptavidin signal among adjacent neurons

formal analysis, S.P