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10.1042/bj1120117 90 KucejovaB.DuarteJ.SatapatiS.FuX.IlkayevaO.NewgardC
While loss of p53 function may weaken the apoptotic signaling response mediated by DNA damage related to chemotherapy resistance [127], thinking about strategies to reduce side effects without compromising p53 function will be of widespread value in cancer treatment

In fact, a meta-analysis of clinical trials found a modest benefit for individuals with mild cognitive impairment, though a separate systematic review concluded more evidence is needed before clinical recommendations can be made

Overall profile health assessment

Hypothermia can also be a manifestation of hyperammonemia [see Warnings and Precautions (5.11)]

A cumulative pain score based on the weight-bearing behavior of the animals was also utilized
