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Dynamic PML Protein Nucleolar Associations With Persistent DNA Damage Lesions in Response to Nucleolar Stress and Senescence-Inducing Stimuli

The HA contents were measured using the following enzyme linked immunosorbent assay (ELISA) protocol: Harvested tissues were stored at 20 C until time of assay

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Although these disorders differ fundamentally from mitochondrial myopathies in their primary metabolic defects, involving cytosolic glycolysis or beta-oxidation rather than mitochondrial oxidative phosphorylation, they share a similar vulnerability to exercise-induced energy depletion, which provides a useful comparative framework

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