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Glutathione S-transferases (GSTs) are the enzymes expressed in the cytosol, microsomes, and mitochondria and catalyze glutathione conjugation to electrophilic compounds, not only produced from exogenous xenobiotics by biotransformation but also arise from endogenous substances

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Open Biol 7(12):170219 Du X, Zhang P, Fu H, Ahsan HM, Gao J, Chen Q (2019) Smart mitochondrial-targeted cancer therapy: subcellular distribution, selective TrxR2 inhibition accompany with declined antioxidant capacity