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The table below shows possible dosage changes for severe cases: Vitamin B12 Injection Dosage for Adults with Malabsorption Adults with malabsorption issues, like those with celiac disease or Crohns disease, might need more B12 injections

For best absorption, take vitamin D with meals and B12 on an empty stomach with water

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3 Extended Administration Pharmacokinetics in DIO Mice Neelakantan et al., Biochemical Pharmacology (2024) This study reported a 28-day once-daily administration protocol of 5-Amino-1MQ in diet-induced obese mice, characterizing plasma pharmacokinetics, tissue distribution, and effects on body composition, fatty liver pathology, and circulating biomarkers

Journal of Investigative Dermatology, 113(3), 364-368

Sublingual Vitamin B12 is used because it is felt to have superior absorption over oral tablets that are absorbed in the GI tract