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In peripheral blood mononuclear cells (PBMCs) of CD patients, hsa_circRNA_103124 expression upregulated significantly, which inhibites aotophagy [43, 44]

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12:e0172161

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These effects help to slow down the aging process and maintain the health and function of the body

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doi: 10.1016/j.cmet.2023.03.010 111 RibotJCLopesNSilva-SantosB

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Exogenous MG exposure (Figure 4) further revealed two distinct ferroptosis-promoting mechanisms: covalent binding-mediated glutathione depletion, which crippled glutathione peroxidase activity, and suppression of selenoprotein biosynthesis, evidenced by diminished GPX4 and SLC7A11 expression (Figure 5)

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doi: 10.1096/fasebj.2018.32.1_supplement.538.4

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