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Mitochondrial Iron Metabolism: The Crucial Actors in Diseases

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Although DMF is a common solvent used in this type of reaction, the high temperatures associated with the presence of tertiary amines (e.g., DIPEA) can result in thermal decomposition of the DMF into a dimethylamine by-product

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Gebicki J.M., Nauser T., Domazou A., Steinmann D., Bounds P.L., Koppenol W.H

Even if BPC-157 survives gastric acid, pepsin and pancreatic proteases remain active in the duodenum and small intestine at physiological pH and will hydrolyze unprotected peptide bonds

10.1021/sb400131a
