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Dysfunction of the UPS is linked to altered sleep timing, reduced circadian rhythm amplitude, and impaired phase resetting, highlighting UPS components as promising targets for correcting circadian disruptions and related disorders

In Graves Disease, theres excessive production of thyroid hormones because the antibodies stimulate the thyroid by activating the TSH receptor [56].

Hashimoto, M

doi: 10.1007/s12011-025-04653-7 138

Additionally, GB enhances antioxidant defense systems, indirectly supporting ion homeostasis by protecting transporters from oxidative damage (Ali et al., 2020)

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Kawakami H., Okamoto I., Arao T., Okamoto W., Matsumoto K., Taniguchi H., Kuwata K., Yamaguchi H., Nishio K., Nakagawa K., et al