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Description
The nasal route was originally developed for Semax because it provides direct access to the brain via the olfactory nerve, bypassing the blood-brain barrier

Nat Rev Mol Cell Biol 6 , 345351 (2005)

Notably, indoleamine 2,3-dioxygenase 1 (IDO1), a pivotal enzyme in tryptophan catabolism, drives immunosuppression by converting tryptophan to kynurenine (Kyn), thereby activating the aryl hydrocarbon receptor (AhR)

Muse, E

G, The European Food Safety Authority (EFSA)

InChi Key: NOIHSRSQDMJJFH-ULEGLUPFSA-L
