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(somatotrophin) is secreted by anterior pituitary cells called somatotrophs

As the thymus involutes, production of thymic hormones including thymosin alpha-1 declines precipitously

Since the liver is the major site of IGF-1 production, when steatosis develops lowering insulin sensitivity, the severity of steatosis at different stages of insulin resistance and metabolic syndrome seems to be correlated with worsened circulating IGF-1 levels [234]

2021;81(13_Supplement):1632

Sikiric et al., 2002, 2016)
