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10.1186/s12967-019-02155-4 J

The primary enzymes/genes of glutathione system (Figure 1) are -glutamylcystiene synthetase ( gshA ), glutathione synthetase ( gshB ), glutathione reductase ( gshR/gor ), and glutathione peroxidase ( gpo )
Hence, the balance between S in glutathione and in proteins may change in conditions that promote cellular oxidation, with flux favoring glutathione synthesis in stress conditions

First, under conditions of nutritional ketosis, -HB constitutes the principal KB in systemic circulation, representing the majority of the dynamic range in circulating ketone concentrations
Antioxid Redox Signal 13:57587

1999) and in the use of CysGly by neurons (Dringen et al