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Once on TPN for extended periods, patients often experience decreased plasma carnitine levels due to insufficient synthesis and supplementation

as described in Schneider et al

Eugene Arnold, MD, MEd, are with the Department of Psychiatry, Ohio State University Medical School, Columbus, OH

doi: 10.21037/tau.2017.09.13 [DOI] [PMC free article] [PubMed] [Google Scholar] 66

(2001) [86] reported that L-Carnitine, acting as a cofactor in fatty acid transport, may have a reparative effect by eliminating elevated intracellular levels of toxic acetyl-coenzyme A or by replacing fatty acids in the phospholipid membrane

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