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Metabolic reprogramming by ex vivo glutamine Inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity

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Differentially localized acyl-coa synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol

doi: 10.1016/j.virs.2023.12.004

Theyre tailored for each patient