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however, this was not seen in PGC-1 -KD cells

doi: 10.1038/s41598-021-87619-8 11

Extended protocols show whether anti-swelling effects persist or increase with continued use

These factors collectively suggest that edaravones therapeutic effect may be most pronounced in a specific subset of ALS patients, and its global applicability requires further careful evaluation

The sealed, sterile environment is stable

Owing to its high concentration in the cell (~10 3 M) 1 , the GSH/GSSG pair acts as the main intracellular redox buffer, plays a key role in the detoxification of reactive oxygen species (ROS), and participates in redox signalling 2