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For example, GSH, CoQ 10 and BH 4 , which Nrf2 depends on for its antioxidant effect, are not conducive to the study of specific molecular mechanisms of ferroptosis due to their broad-spectrum effects (Chen et al

Potential therapies targeting ferroptosis are summarized in Table II

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In research contexts, the complex has been explored for its potential to support extracellular matrix maintenance, barrier quality, and tissue remodeling signals, particularly when formulated for topical presentation