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Recently, a second cardiac K ATP channel complex has been identified at the surface of cardiomyocytes, consisting of a Kir6.1 pore-forming subunit that displays constitutive, rather than ATP-dependent, activity (Brennan et al., 2024)

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Another emerging class of drugs with dual incretin agonistic effects is currently being developed for treating type 2 diabetes patients with chronic kidney disease and NASH

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