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It is noteworthy that NRF2 regulates the expression of enzymes necessary to synthesize GSH, including glutamate-cysteine ligase catalytic subunit (GCLC) and its regulatory subunit (GCLM), glutathione reductase (GR), glutathione peroxidase (GPx), and several glutathione S-transferases (GST) (Suh et al

For the last 20 years, Sekhar has been studying natural aging in humans and animal models to understand why age-related declines occur and how to correct them

The balance between GABA and other neurotransmitters, such as Glutamate, is crucial for normal brain function, and an imbalance can lead to neurological disorders

The cells were treated with either water (control) or 2-AB at varying concentrations overnight

Tan et al., 2022)

Its no surprise that there was a similar effect, since they had very similar L-dopa levels in the blood