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Approximately 40 APP mutations and co-localization of proteins with A [103] responsible for causing AD have been identified

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The parameters of GO analysis were set as follows: min overlap = 3, p-value cutoff = 0.05, min enrichment = 1.5

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Funding/support: Funding for the medical writing and editorial assistance was provided by Mylan Specialty LP

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The amount of calcium entering a spine during synaptic activity therefore depends on the depolarization of the spine head

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