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The effect of L-arginine supplementation on blood pressure in adults: A systematic review and dose-response meta-analysis of randomized clinical trials

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specificity 60% from 83%) (Table 5a and b)

Pathway enrichment analysis further revealed significant activation of multiple signaling cascades, including the Hippo, PI3K (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform)-Akt (protein kinase B), and MAPK pathways (Fig

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