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(2019) mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis

Beyond GSH metabolism, Nrf2 also promotes intracellular NADPH generation by upregulating the expression of genes related to the pentose phosphate pathway, which contains the key enzyme G6PD, as well as genes involved in pyruvate cycling and folate metabolism (166)

Results and Discussion 3.1

Neuron 59, 634647

doi: 10.1186/s40035-020-00199-x

Insights in the etiopathology of galactosyltransferase II (GalT-II) deficiency from transcriptome-wide expression profiling of skin fibroblasts of two sisters with compound heterozygosity for two novel B3GALT6 mutations