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It is essential to mention that the search was conducted in 2023 to mitigate any potential bias stemming from database updates

Volume, not dose

By absorbing and dissipating UV rays, melanin prevents DNA damage that can lead to skin cancer

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The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis