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Our previous studies showed that selective 5-HT 1A agonists (e.g., 8-OH-DPAT) ameliorated haloperidol-induced EPS (e.g., bradykinesia and catalepsy) and reversed the striatal Fos protein expression by the haloperidol treatment (Ohno et al., 2008a

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Science 122 , 501514 (1955)

In hippocampal neuron cultures, Dihexa promoted synapse formation at picomolar concentrations, providing cellular-level evidence for its cognitive mechanism
