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The profound function of H 2 0 2 is illustrated by catalase, which restores the spontaneous induction of tyrosine phosphorylation in capacitating mammalian spermatozoa, and hence, reduces functions, such as hyperactivation, acrosomal exocytosis, and sperm-egg fusion

Principal component analysis (PCA) and t-distributed stochastic neighbor embedding (t-SNE) were performed utilizing the Rtsne (version 0.16) and stats (version 4.1.1) R packages to assess the distribution of various groups

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However, their clinical translation is limited by challenges in intracellular delivery to target cells and the potential for off-target gene silencing effects in non-target tissues