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In the hypoxic TME, stabilization of HIF-1 not only enhances glycolytic flux through the upregulation of HK2 and PDPK1, but also supports tumor cell motility and invasiveness (77)

Elevated levels of trimethylamine oxide in muscles of deep-sea gadiform teleosts: a high-pressure adaptation

Cell Cycle Progression of Glutathione-Depleted Human Peripheral Blood Mononuclear Cells Is Inhibited at S Phase

MGO has the potential to disrupt the proper functioning of astrocytes [320] and activate inflammatory pathways through the stimulation of microglia [321,322]