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The aim of the present report was to synthesize and to purify both APAP- and PAP-cysteine conjugates and, as the first study at all, to evaluate their biological effects in human kidney HK-2 cells in comparison to parent compounds

In addition, autophagy appears to be the primary mechanism by which selenium ions are detoxified

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This comprehensive metabolic shift results in enhanced lipid utilization (lower cellular fat accumulation) and an efficient use of nutrients, echoing the metabolic effects of calorie restriction or exercise at the cellular scale