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Description
Reports also describe shrinkage of adipocyte size and reductions in fat-pad mass while preserving insulin signaling markers in certain models
Additionally, there is some evidence that suggests it may play a role in the homocysteine metabolism, thereby offering potential cardiovascular benefits, although again, more research is necessary to validate this use

The IGF1R binds IGF1 and IGF2 with high affinity and the IR binds insulin with high affinity

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The CKGGRAKDC targeting sequence finds and binds to the PHB1-ANXA2 receptor complex on endothelial cells of white fat vasculature
