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doi: 10.1007/s11033-020-06084-0 55 UddinSJAfrozMZihadSMNKRahmanMSAkterSKhanINet al

41 In these studies, VSL#3 (containing four species of Lactobacilli , three of Bifidobacteria and Streptococcus thermophilus ) was the most commonly used probiotic product in the clinical trials
A double stranded small-interfering RNA (siRNA) to the ANGPTL3 mRNA, that is conjugated to GalNAc (identified as ARO-ANG3), has shown promise at hepatocyte-specific reduction in ANGPTL3 mRNA levels
References Belay B, Esteban-Cruciani N, Walsh CA, Kaskel FJ

Bromelain: An enzyme extract from pineapples that reduces inflammation and aids in fat reduction

found that there were significant higher apoC3 in HDL particle from CAD patients compared to healthy controls
