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In cases of less severe reactions, the injection should be paused and the patient should be treated to relieve their symptoms

Joseph, M

doi:10.1016/0022-4731(87)90200-7
2023;390 doi: 10.1016/j.biortech.2023.129803

Whether this is cause for concern depends on other factors

Metal ion formulations for DMEM and DMEM/F12 (Supplementary Table 1) include iron (Fe 3+ ), zinc (Zn 2+ ), copper (Cu 2+ ), and magnesium (Mg 2+ )
