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These include peripheral vasodilation, increased cardiac output, a change in the oxygen-hemoglobin dissociation curve that facilitates oxygen unloading in the tissues, and shunting of blood away from circulation-rich organs (e.g., gut, skin, kidney) to critical organs (e.g., heart, brain)

doi: 10.1007/s00018-022-04341-y 40 DandekarAMendezRZhangK
Glucocorticoids mediate circadian timing in peripheral osteoclasts resulting in the circadian expression rhythm of osteoclast-related genes
doi: 10.3390/ijms23031445 9 AlbertM

[DOI] [PMC free article] [PubMed] [Google Scholar] 428.Mller M., Munn-Bosch S

This shift reduces its exposure to the ubiquitin-proteasome system (UPS), as the cytosolic form is more susceptible to ubiquitination and subsequent degradation ( Figure 1B )