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Based on heterologous expression systems and to express lipase fitment problem, can use bioinformatics, synthetic biology, systems biology, such as thoughts and technical means, through the prediction and design effective reform way, reconstruct metabolic network, optimize the integration of different fine properties such as strategy, build efficient expression of heterologous lipase system, By optimizing the key technological factors and process regulation in the lipase production process, the optimal control technology of the lipase production process was determined, and the stable and efficient production of exogenous lipase was realized, so that the lipase was developed satisfactorily in industry

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