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11,25 Across the studies that reported serious/severe AEs, serious events were rare (2 in the treatment arm and 1 in the control) and, when adjudicated, not attributed to ALC

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Advanced imaging modalities, like functional MRI and dynamic PET-CT, provide real-time imaging of glymphatic and vascular interactions and enable the clinician to dynamically develop clinical treatment [347]

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doi: 10.1016/j.neubiorev.2015.07.015 [DOI] [PubMed] [Google Scholar] 419

GLS inhibition (e.g., via BPTES) significantly reduces cell viability, demonstrating potent antitumor effects, especially in AR-independent cell lines (236, 237)