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Excess caffeine consumption increases urine production, leading to accelerated loss of these vital nutrients alongside essential minerals through increased urination

More specifically, Fyn phosphorylates NRF2 at Tyr568 leading to nuclear export, ubiquitination, and degradation of NRF2 [236]

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These molecules act as signals that recruit inflammatory cells, including neutrophils and macrophages, to the site of cell death, exacerbating local inflammation and potentially contributing to miscarriage ( 5.3 Evidence of ferroptosis in RM pathophysiology Emerging studies support the involvement of ferroptosis in RM, highlighting its potential role in pathophysiology through various lines of evidence