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The Gut-Brain-Immune Axis Modern functional medicine recognizes that gastrointestinal health is inseparable from neurological and immune function

How it works: Epitalon is a synthetic version of epithalamin, a substance from the pineal gland studied by Russian gerontologist Vladimir Khavinson

Suspected neurological involvement due to B12 deficiency warrants urgent initiation of treatment and may require specialist referral

This has led to a surge in gray market research chemicals

Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)

Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
