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IV drips typically feel faster because they deliver fluids and vitamins directly into the bloodstream and include hydration

70 In contrast, a recent meta-analysis indicated that after up to 4 months of use of metformin, diabetic patients vitamin B 12 levels were reduced by an average of 57 mol.l 1

In certain regions of the world, marginal or subclinical vitamin B 12 deficiency may be fairly common in other age groups as well, including children, premenopausal women, and pregnant women, primarily due to low intake of animal-source foods (reviewed in 5)

A typical therapeutic dose for humans ranges from 0.25 to 2 mL per injection

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