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Meta-analyses were performed using random-effects models
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In Ang II-challenged mice, the vascular media thickness, media-to-lumen ratio, and collagen deposition were reduced by 26.19%, 27.05%, and 30.40%, respectively, following intragastric administration of NMN, and elastin expression was restored by 24.38% after NMN treatment (Supplementary Fig
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NF - B pathway: inhibits NF - B p65 nuclear translocation, reduces I B phosphorylation, blocks osteoclast activation and bone resorption function
