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10.1007/s11357-017-9966-x 36 Powell-BraxtonL.HollingsheadP.WarburtonC.DowdM.Pitts-MeekS.DaltonD.et al (1993)

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Another metaanalysis of randomized clinical trials showed that magnesium supplementation led to drops in blood pressure in participants with hypertension - enough to lower cardiovascular risk (Frontiers in Physiology, 2024)

5.2.2 Limitations due to the disease The pathophysiology of mutations or mechanisms underlying the neuronal pathology of mitochondrial diseases is still unknown in most patients, which makes it difficult to interpret the mitochondrial or neural readout in pharmacological screenings