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Then, antimicrobial agents will be limited according to the result of the culture for controlling the source of the infection [9] Fluid therapy: For ameliorating hypotension and decreased mean arterial pressure (MAP), the Surviving Sepsis Campaign (SSC) recommended that 30 mg/kg fluid should be administered initially [2] Target blood pressure: Low MAP is related to more mortality rate and kidney injury

P = 0.004

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The hypothalamic-pituitary-gonadal axis governs this entire cascade

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