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doi:10.1073/pnas.1820171116

PubMed Rothman, K.J., et al
As a result of the absence of corresponding histologic landmarks in the oral mucosa (ie, papillary and reticular dermis), Clark levels of cutaneous melanoma are not applicable to those of the oral cavity
In a preclinical study, vupanorsen reduced levels of hepatic ANGPTL3 and TGs, circulating TG and LDL-C levels, and the progression of atherosclerosis [40]