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Wang and collaborators modified star poly(lactic-co-glycolic acid) ends with -lipoic acid to obtain a new nanoparticle with enhanced loading capacity, reduced drug leakage, and efficient uptake in melanoma cells [154,155]

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It reduces contamination risk but does not prevent chemical degradation of the peptide
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83 Hypotheses for the mechanism include Distal parenchymal embolization from dislodged mural thrombus, 86 Compression or kinking of associated renal artery branches, Hemodynamic changes from turbulent blood flow within the aneurysm resulting in decreased distal renal artery perfusion, 83 which can induce renin-dependent hypertension

Genomation: a toolkit to summarize, annotate and visualize genomic intervals
