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However, in a recent study in 106 patients with alcohol use disorder with variable degrees of liver disease, intestinal permeability normalized after a 3-week detoxification program, while markers of bacterial translocation (LBP) remained elevated (149)

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Though the cause of ME/CFS is unknown, research indicates that 60-70% of cases are associated with viral infections (e.g., Epstein-Barr virus, H1N1, human herpesvirus, etc.).27 But the persistent symptoms experienced by long COVID patients are so similar to those seen in ME/CFS that some experts have proposed that long COVID may actually be another post-viral example of ME/CFS instead of a separate condition.28 While there appear to be a few different subtypes of ME/CFS,29 30 it stands to reason that patients with cases caused by COVID, or those most like long COVID, may see a similar restoration of an appropriate response from TA-1 peptide therapy as noted in the aforementioned ex vivo study.26 However, as with long COVID, far more research is needed to evaluate TA-1 as a potential treatment for ME/CFS