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Christian Neumann, Charit Medical University of Berlin, Germany Updates Copyright 2021 Kinashi and Hase

Mid-protocol check (week 4-6): Retest inflammatory markers (hs-CRP, ESR) and copper/ceruloplasmin

All experimentation, handling, and storage must follow applicable institutional and regulatory standards

Does magnesium calm the brain

Intravesical treatments with heparin, hyaluronic acid, chondroitin sulfate, bacillus Calmette-Guerin, dimethylsulfoxide, and resiniferatoxin have been effective in treating IC/BPS, but the effects were not durable (Hanno et al., 2015)

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