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In this landmark paper, Braak and colleagues first introduced the concept of spreading of pathology in the parkinsonian brain

H 2 O 2 neutralization prevents the production of hydroxyl radicals in the body, which can harm biomolecules via the Fenton reaction 68

LB-01 functionally mimics glutathione's protective role , but is more tissue penetrant and better at reducing disulfides than other protective monothiols

DAPI was used to stain nuclear DNA

Although much remains to be discovered, the primary theoretical pathway through which Parkinsons disease spreads was hypothesized by Braak and colleagues (Rietdijk et al., 2017

doi: 10.1179/147683008X301360 22 AnhNKThuNQTienNTNLongNPNguyenHT