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Clinical data insights: In a large placebo-controlled trial, tesamorelin raised IGF-1 by 181% on average, but about 5% of participants discontinued due to adverse events, most commonly musculoskeletal pain and injection-site irritation (Falutz et al., NEJM )

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As the body reaches the recovery plateau well above the asymptomatic level but not at the pre-crash level, the body is allowed to rest