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The proliferation of tumor cells and immune cells depends on glycolysis, and tumor cells compete for glucose, which makes immune cells lack nutrients and unable to perform their functions (81)

For instance, elevated expression of its target gene LOC554202 (hosting oncogenic miR-31), has been observed in lung cancer tissues compared to adjacent normal tissues, correlating with poor prognosis [133]

Yes, liposuction doesnt affect breastfeeding since it targets localized fat and doesnt interfere with milk production or hormones.

Therefore, the CS regulation, at both enzymatic and epigenetic levels, plays a pivotal role in tumors, suggesting new druggable pathways for prevention and treatment of human cancer

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