glutathione reductase free radical scavenger system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis A schematic diagram showing the
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Figure 3 Direct activation of mast cells Many small molecule drugs directly activate mast cells in an IgE-independent manner, which can immediately provoke the degranulation of mast cells and initiate the rapid release of multiple inflammatory mediators, such as histamine, tryptase, serotonin, heparin, and proteases

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doi: 10.1038/nrgastro.2017.20 6 AmabebeE.RobertF

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