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10.1021/acs.molpharmaceut.3c00769 98 TakedaA.HamanoS.YamanakaA.HanadaT.IshibashiT.MakT

The attenuation of insulin/IGF-1 signaling is not only associated with increased lifespan but there is convincing evidence that it can alleviate many age-related diseases, such as cancers, cardiovascular diseases, osteoporosis, and neurodegenerative diseases
Cotinine is produced when the body metabolizes nicotine after tobacco or nicotine product use
In oxidative phosphorylation, the respiratory chain protein complexes facilitate the generation of a proton motive force (PMF) across a biomembrane, which is then harnessed by ATP synthase to produce ATP

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Similarly, water generates wood is equaled to kidney generates liver, this indicates that the kidney is mother organ, and the liver is child organ
