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GSH / GSSG balance is crucial for homeostasis, stabilizing cellular biomolecular spectrum, and facilitating cellular performance and survival

The liver from Gclc L-KO mice showed rapid depletion of Gclc mRNA and progressive loss of GCLC protein and GSH levels (Fig

Brain Vitamin E Deficiency During Development Is Associated with Increased Glutamate Levels and Anxiety in Adult Mice

58 Antioxidant-enzyme interaction in diabetes Diabetes, as a metabolic disorder, is associated with an imbalance between the generation of ROS and the antioxidant defense system

Furthermore, functional interrogation of the corresponding importance of pathways downstream of NRF2-dependent transcription in cancer remains limited

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