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Hearn, Manccy L
There are several possible reasons for this failure
Sources 1 National Center for Complementary & Integrative Health
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Matrix-assisted laser desorption ionization mass spectrometry with 2-(4-hydroxyphenylazo)benzoic acid matrix
Finally, succinate was shown to bind to SUCNR1 on tumour cells and suppress factors that facilitate T cell trafficking into to the tumour 69 , thereby reducing anti-PD1 efficacy, whereas in vitro succinate treatment of CAR T cells improved its effector function 61
